The Department of Health Sciences is pleased to announce the first seminar in our 2023-24 Health Sciences Seminar Series, and this event will be held in-person with the option to attend via Zoom (see registration information below).

Targeting the IAPs for cancer immunotherapy

Evasion of cell death is recognized as one of the key hallmarks of cancer. The Inhibitor of Apoptosis (IAP) gene family are key oncogenes found in many solid and blood cancers. Consequently, targeting the IAPs is a promising therapeutic approach against cancer. A class of drugs called SMAC mimetics have been developed to antagonize the function of the IAPs. I will highlight our recent research into understanding the mechanism of SMAC mimetic efficacy and of the potential of this class of IAP antagonists to potentiate immune-based therapies for the treatment of cancer.

Presenter:
Dr. Shawn Beug
Canada Research Chair (Tier 2)
Scientist, CHEO Research Institute
Assistant Professor, uOttawa, Department of Biochemistry, Microbiology and Immunology

Zoom registration - https://carleton-ca.zoom.us/meeting/register/tJYrcumgrjkvH9X0mRzPppLRkGvGvY7ARhyU